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KMID : 0604520080340030175
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Journal of the Society of Cosmetic Scientists of Korea
2008 Volume.34 No. 3 p.175 ~ p.181
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Preparation of Cellulose Nanoparticles Loaded with Retinyl Palmitate
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Lee Jeong-Soon
Ma Sang-Chol
Kang Ki-Choon
Pyo Hyeong-Bae
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Abstract
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Cellolose nanoparticles loaded with retinyl palmitate were prepared by modified spontaneous emulsification solvent diffusion method. We used polysorbate 20, polysorbate 60, and PPG-26-Buteth-26/PEG-40 Hydrogenated castor oil as dispersion medium. The optimum condition for particle size of cellulose nanoparticles was 1w/v% ethyl cellulose with, 3w/v% polysorbate 60 solution. And The optimum condition for leading amount of retinyl palmitate of cellulose nanoparticles was 2w/v% ethyl cellulose with 1w/v% polysorbate 60 solution. Also, we found that this optimum condition can be applicable to other active compounds.
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KEYWORD
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nonoparticle, cellulose, retinyl palmitate, modified spontaneous emulsification solvent diffusion method, polysorbate 60
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